Let me tell you what the worst weather combinations are: cold temperatures with dry air and Hot temperatures with high humidity.
With cold weather, everything is obvious cold, but combine that with dry air, that makes things even colder and will dry out your skin causing a lot of skin related problems.
The hot temperatures you normally expect can make thing unbearable Hot, but combined that with high humidity, that makes everything feel a lot more muggy and insufferable causing everything to swear a lot more and be completely drench while also increasing the chances of getting a heat stroke.